| |
| |
| Parenteral |
| GI INFECTIONS AND BOWEL STERILIZATION |
| Adult:
As colistimethate sodium: 6 million units by IM or slow IV inj/infusion given daily in 3 divided doses. Max: 6 million units in 24 hr. |
| |
| Oral |
| GI INFECTIONS AND BOWEL STERILIZATION |
| Child:
As sulfate: 15-30 kg: 0.75-1.5 million units tid; <15 kg: 0.25-0.5 million units tid. |
| |
| Oral |
| GI INFECTIONS AND BOWEL STERILIZATION |
| Adult:
As sulfate: 1.5-3 million units tid. |
| |
| Parenteral |
| GI INFECTIONS AND BOWEL STERILIZATION |
| Child:
As colistimethate sodium: >60 kg: 6 million units/day given in 3 divided doses. ≤60 kg: 50,000 units/kg/day in 3 divided doses. Max: 75,000 units/kg/day. |
| |
| Inhalation |
| AS AN ADJUNCT TO SYSTEMIC ANTIMICROBIAL THERAPY IN RESPIRATORY INFECTIONS |
| Adult:
As colistimethate sodium: 1-2 million units bid-tid. Max: 2 million units tid for up to 3 mth in frequent recurrent infections. 1-2 million units bid may be used for long-term therapy. |
| |
| Inhalation |
| AS AN ADJUNCT TO SYSTEMIC ANTIMICROBIAL THERAPY IN RESPIRATORY INFECTIONS |
| Child:
As colistimethate sodium: <2 yr: 0.5-1 million units bid; ≥2 yr: 1-2 million units bid, up to 2 million units tid for frequent recurrent infections. |
